New cancer prevention guidelines are urging people to skip the booze entirely.
"For the first time they're saying not one drink a day for women, not two drinks a day for men," ABC News chief medical correspondent, Dr. Jennifer Ashton said.
"They’re saying the best thing you can do for your health is to avoid alcohol completely."
The organization's previous guidelines suggested permitting one alcoholic drink per day for women and two for men. The ACS defines an alcoholic drink as 12 ounces of regular beer, 5 ounces of wine, or 1.5 ounces of 80-proof distilled spirits.
The is the first time the ACS has updated their guidlines since 2012.
In addition to not drinking alcohol, the ACS said people should exercise more and eat fewer process foods and red meat.
The organization said getting 300 minutes or more of exercise per week will "give you the most health benefits."
According to the new guidelines, teenagers and children should at least get one hour of exercise each day.
When it comes to nutrition, the ACS recommended a diet filled with "colorful" fruits and vegetables. People should eat whole grains and brown rice.
The organization also suggests limiting the amount of red meats such as beef, pork, and lamb, processed meats (such as bacon, sausage, and deli meats), other highly-processed foods, and sugar-sweetened beverages.
According to the CDC, cancer is the second leading cause of death in both women and men in the United States.