Bryce was just 19-years-old and driving from college at Chico State to his parents home in Orange County.
His car found crashed in a ditch off Lake Hughes road by the boat launch at Lake Castaic. No sign of him.
His mother says he had taken someone else's prescription for attention deficit disorder.
Everything he owned was left in the car.
Searches of the lake, surrounding areas turned up nothing.
Bryce is 6 feet tall with bright red hair.
Anyone with information is urged to call Crime Stoppers.