Migrant caravan from Honduras heading toward Guatemala, then on to the US border

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San Pedro Sula, Honduras — Hundreds of migrants began walking Wednesday night from this city in northern Honduras toward the Guatemala border, testing a well-trod migration route now in times of the novel coronavirus. Calls for a new migrant caravan to leave from the San Pedro Sula bus station October 1 had been circulating on social media for weeks.

The caravan comes just two weeks after Guatemala reopened its borders after keeping them sealed for months to slow the spread of COVID-19.

But the majority of the migrants who gathered Wednesday decided not to wait for October, instead setting out in the dark of night carrying knapsacks and many wearing masks.

The groups quickly strung out along the highway with some catching rides while others continued to walk toward the Guatemala border.

Mexico asks U.S. to "clarify" hysterectomies on migrant womenLate Wednesday, Guatemala's immigration agency said in a statement that its counterpart in Honduras said about 900 migrants were in the city of Choloma and were headed to the border crossing at Corinto.

Governments throughout the region made it known they were watching Wednesday. Mexico's immigration agency said in a statement that it would enforce "safe, orderly and legal" migration and not do anything to promote the formation of a migrant caravan. The U.S. Embassy in Honduras said via Twitter Wednesday that migration to the U.S. was more difficult than ever right now and more dangerous because of COVID-19.

The flow of migrants north from Central America had slowed dramatically during the pandemic as countries throughout the region closed their borders. Most migrant shelters along the principle routes north through Mexico closed their doors to new arrivals as they tried to keep the virus from spreading to vulnerable migrant populations. Mexico and the United States deported hundreds of migrants back to their home countries to try to empty detention centers.

The U.S. government used the pandemic to effectively shut down the asylum system at its southern border, but as CBS News immigration reporter Camilo Montoya-Galvez reported in early September, apprehensions of unauthorized migrants along the southern border rose for a fourth consecutive month in August, with U.S. immigration authorities making nearly 50,000 arrests and expelling the majority of those apprehended under coronavirus restrictions.

Mexico has tried for months to bus asylum seekers stuck at its northern border south. Mexico has typically offered migrants the opportunity to seek asylum there, but many have their minds set on the United States.

Migrants are also likely to find it more difficult to find work in Mexico now as the economy is expected to contract 10% this year due to the impact of the pandemic.

The departure of the group Wednesday night was reminiscent of a much larger migrant caravan that formed two years ago shortly before U.S. midterm elections. It became a hot issue in the campaign, fueling anti-immigrant rhetoric.

Under pressure from the U.S. government last year, Mexico took a more aggressive approach toward migrants. It deployed its National Guard to intercept them on highways and worked to keep massive caravans seen in previous years from forming.

Central American migrants began travelling in large groups in recent years, seeking safety in numbers and in some cases avoiding the cost of smugglers. They drew significant attention, but were a fraction of the everyday migration flow toward the U.S. border.