The company announced the much-anticipated device is now available for preorder from Verizon and will hit stores on May 16.
It's a major milestone for both Samsung and Verizon: It'll be first time anyone can buy a phone that runs on ultra-fast 5G wireless networks. 5G boasts faster load times and will help power tech like self-driving cars and virtual reality.
While 5G won't work everywhere, Verizon's 5G network is expanding. The company on Thursday also named 20 more cities in the United States, including Atlanta, Boston, Houston and San Diego, where customers will have access to its 5G "Ultra Wideband" network. Verizon says its 5G Ultra Wideband network offers much faster download times than 4G LTE.
Although Verizon customers will get first dibs on the 5G smartphone, the phone is expected to launch on other major carriers soon.
The Galaxy S10 5G costs $1,299.99 for 256 GB storage and $1,399.99 for the 512 GB option.
The device could give Samsung a competitive advantage in early 5G markets, which includes parts of the US and South Korea. (Apple isn't expected to have a 5G phone until late 2020).
But the transition from 4G to 5G networks won't be widespread until 2020 and will require infrastructure upgrades totaling billions of dollars. This could limit the Samsung phone's full potential.
Wireless carriers are racing to grow their 5G networks. AT&T -- CNN's parent company -- offers it in more than a dozen cities. Sprint and T-Mobile are planning to launch 5G coverage this year.
Previously, Verizon said it would roll out 5G to over 30 US cities this year, along with expanding its 5G home broadband internet service.