Week 5 of the 2019 NFL season was historic from a Fantasy Football sense. To say that Week 6 has a shot to be historic just from a pure football sense may feel a bit hyperbolic. But it could help to determine two of the NFL's tightest divisional races, may be the best chance for one team to avoid a winless season, and could decide who has the No. 1 overall pick in the 2020 NFL Draft.
Here's a look at the three most intriguing matchups of Week 6:
1. Washington Redskins at Miami Dolphins
You may have to change your definition of intriguing to truly be excited about watching this game, but it may prove to have long-term implications.
The Miami Dolphins, coming off of a Week 5 bye, have a -137 point differential through their first four games of 2019. They've found themselves at No. 32 in every edition of the RADIO.COM NFL Power Rankings. If their first four games have been any indication, the 2019 Dolphins, perhaps by design, may be remembered as the worst team in NFL history.
That said, the 0-5 Washington Redskins became the first team to fire their head coach in 2019, dismissing Jay Gruden after a loss to the New England Patriots last Sunday. Since taking a 17-0 lead on the Philadelphia Eagles in Week 1, the Redskins have been outscored 151-56 by opponents. They checked in just one spot above the Dolphins on this week's RADIO.COM NFL Power Rankings.
Beyond football fans getting some sort of sick enjoyment out of watching perhaps the two worst teams in the sport, the loser of this game, especially if it's the Dolphins, feels at risk of becoming the third team to finish a season 0-16.
Part of the strategy from the Dolphins in attempting to bottom out was to secure the No. 1 pick. They can then draft (probably) Alabama quarterback Tua Tagovailoa, and hopefully solve the quarterback position for the first time since Hall of Famer Dan Marino retired after the 1999 season. A loss to the Redskins would put that in jeopardy, and it's hard to say with certainty that Daniel Synder's team wouldn't consider using another first-round pick on a quarterback next year.
2. San Francisco 49ers at Los Angeles Rams
If you expected the San Francisco 49ers to start to regress on Monday Night Football after a Week 4 bye week, you weren't alone. And you weren't alone in being very wrong, as the 49ers trounced the Cleveland Browns 31-3 to move to 4-0 in 2019.
While Kyle Shanahan is viewed as one of the best offensive minds in the NFL, it's been the 49ers defense that's led to their success thus far. 2019 first-round pick Nick Bosa led the 49ers in Week 5, recording two sacks of Baker Mayfield. Bosa and DeForest Buckner lead a defense that's currently the No. 3 overall unit in the league.
The 49ers defense will face their biggest test yet in Week 6, as they'll face the defending NFC Champion Los Angeles Rams. While the division-rival Rams have lost two consecutive games, they've scored 69 points combined in those two losses. Sean McVay's offense has still been a top five unit during the first five weeks of the 2019 season.
This, of course, is the first of two meetings between the 49ers and Rams. In a crowded NFC West, each game may prove to be crucial. Beyond the 49ers and Rams, the Seattle Seahawks are 4-1 and Russell Wilson is playing at an MVP caliber level.
3. Detroit Lions at Green Bay Packers
One of the biggest surprises of the first quarter of the NFL season was the Detroit Lions. They did blow a 24-6 lead in Arizona in Week 1 and ultimately tied the Cardinals, but since then they've defeated the Los Angeles Chargers and Philadelphia Eagles, while pushing Patrick Mahomes and the Kansas City Chiefs in a 34-30 Week 4 loss.
After their bye week, the Lions don't get to ease back into things. They'll head to Lambeau Field for a Monday Night Football showdown with the 4-1 Green Bay Packers, who skyrocketed in the latest RADIO.COM NFL Power Rankings.
Following a Week 4 loss to the Philadelphia Eagles on Thursday Night Football, the Packers traveled to Dallas, and as Aaron Rodgers-led teams tend to do against the Cowboys, they left with their fourth victory in hand. They've made as good of an early impression as any team in the NFC.
This matchup takes on additional importance with the understanding that the NFC North may be the best division in the NFL. The Lions are 2-1-1. The Packers are 4-1. And even if it's felt like their respective seasons have already bordered on disaster, the Minnesota Vikings and Chicago Bears are both 3-2.