Two of the three lanes of Canal Street upbound (lakebound) closed at 7am Monday.
The lanes are between North Pierce and Carrollton are closed for repairs to the drinking water system.
S&WB says the work is the repairs will restore two 24-inch water valves.
The department uses valves throughout the city to manage or reroute the flow of drinking water with the intention of supplying continuous service to customers while making repairs or responding to emergencies.
While the far-right, curbside lane will be open, S&WB advises drivers to avoid the area as much as possible until the work is completed and the roadway reopened late Wednesday afternoon.